Role of Microorganisms in male infertility

•Microbial infections have been reported to reduce sperm viability. Infections of the male genitourinary tract account for up to 15% of cases of male infertility (F. Balen van and T.Gerrits 2003). Acute and chronic infections and consequent inflammation in the male reproductive system may compromise the sperm cell function and the whole spermatogenetic process (W. Ombelet et al., 2003) causing qualitative and quantitative sperm alterations. Staphylococcus aureus is the most prevalent Gram positive organism, while Escherichia coli is the most prevalent Gram negative organism isolated in the semen of males with primary infertility. Chronic epididymitis secondary to Chlamydia trachomatis infection had been shown to blockage of the epididymis and thus obstructive azoospermia. However, Ureaplasma urealyticum infections induce leukocytospermia and consequently lead to sperm damage, decrease sperm counts and invariably impaired sperm motility.

Role of Microorganisms in male   infertility

•Herpes simplex virus (HSV) was reported to have been found in the semen of some infertile men and was related to low sperm count and poor motility. Mumps viral infections in adolescent and adult males carry about 30% risk of developing orchitis or epididymitis, which can result in testicular atrophy and sterility.